Healthcare providers should immediately notify both infection control personnel at their healthcare facility and their local or state health department in the event of a PUI for 2019-nCoV. State health departments that have identified a PUI should immediately contact CDC’s Emergency Operations Center (EOC) at 770-488-7100 and complete a 2019-nCoV PUI case investigation form available below.
如出现2019-nCoV的疑似病例,医护人员应立即通知所在医疗机构负责感染控制的人员及所在地或所在州的卫生部门。发现疑似病例的州卫生部门应立即致电770-488-7100,与国家疾病控制中心的卫生应急中心(EOC)联系,并填写如下2019-nCoV 疑似病例病例调查表。
CDC’s EOC will assist local/state health departments to collect, store, and ship specimens appropriately to CDC, including during afterhours or on weekends/holidays. At this time, diagnostic testing for 2019-nCoV can be conducted only at CDC.
卫生应急中心将协助当地/州的卫生部门适当地收集、存储、运送标本到国家疾病预防控制中心,包括节假日和休息时间。目前,在国家疾病预防控制中心进行2019-nCoV的诊断检测。
Testing for other respiratory pathogens should not delay specimen shipping to CDC. If a PUI tests positive for another respiratory pathogen, after clinical evaluation and consultation with public health authorities, they may no longer be considered a PUI. This may evolve as more information becomes available on possible 2019-nCoV co-infections.
对其他呼吸道病原体的检测标本也应及时向国家疾病预防控制中心运送。如果某疑似病例的标本中另一种呼吸道病原体检测呈阳性,并经过临床评估和公共卫生部门确定后,方可排除。这一条准则会随着2019-nCoV合并感染的更多证据的出现而进行更新。
For biosafety reasons, it is not recommended to perform virus isolation in cell culture or initial characterization of viral agents recovered in cultures of specimens from a PUI for 2019-nCoV.
出于生物安全考虑,不建议通过细胞培养分离病毒,也不建议对2019-nCoV的疑似病例标本培养物中回收的病毒制剂进行初始表征。
To increase the likelihood of detecting 2019-nCoV infection, CDC recommends collecting and testing multiple clinical specimens from different sites, including two specimen types—lower respiratory and upper respiratory. Additional specimen types (e.g., stool, urine) may be collected and stored. Specimens should be collected as soon as possible once a PUI is identified regardless of time of symptom onset. Additional guidance for collection, handling, and testing of clinical specimens is available.
为了提高检测2019-nCoV感染的准确度,国家疾病预防控制中心建议从疑似病例不同部位收集和检测多个临床标本,包括两种标本类型——下呼吸道和上呼吸道。可以收集和存储其他类型的标本(例如,粪便、尿液)。一旦为确诊病例,无论症状发作的时间,都应尽快收集标本。可参照有关收集、处理、检测临床标本的其他指南。
(邓睿 编译)